The HEAL-IST Trial is recruiting participants to evaluate the safety and effectiveness of a hybrid sinus node sparing procedure to treat patients with symptomatic drug refractory or drug intolerant inappropriate sinus tachycardia or IST.
IST is a complex heart condition that occurs in otherwise healthy younger people and causes rapid heart rates of over 100 bpm, even at rest.
Common symptoms of inappropriate sinus tachycardia include:
These symptoms can affect day-to-day activities and can diminish one’s quality of life. There are currently no FDA-approved therapies to treat inappropriate sinus tachycardia. However, a hybrid sinus node sparing ablation is being studied as a potential new treatment option for patients who suffer from symptomatic, drug-resistant or intolerant IST.
Postural Orthostatic Tachycardia Syndrome (POTS) is another type of heart condition. Although patients with POTS can experience similar symptoms to inappropriate sinus tachycardia like lightheadedness, shortness of breath, fatigue and anxiety, a key difference between POTS and IST is resting heart rate. Individuals with POTS typically have a resting heart rate of 90 bpm or less, whereas those with IST have a resting heart rate usually greater than 100 bpm.
Dr. Rani Kronenberger (University Hospital, Brussels, Belgium) describes key differences between IST and POTS and introduces the hybrid ablation procedure to treat IST.
To be considered for the HEAL-IST Trial:
Your trial doctor or research staff will determine if you qualify for the HEAL-IST Trial. Click Here for the Patient Information Guide.
A novel sinus node sparing procedure is being evaluated in the HEAL-IST Trial. Designed to spare the sinoatrial node, the heart’s natural pacemaker, this procedure involves creating lesions along certain areas of the heart’s outside surface and sometimes inside the heart with the goal of lowering the rapid heart rate responsible for IST.
Drs. Chad R Brodt, Gaurang D. Gandhi, Anson M Lee, and Thomas M Beaver discuss why they are passionate about treating patients with symptomatic inappropriate sinus tachycardia.
Drs. Chad R. Brodt, Anson M. Lee and Thomas M Beaver provide a historical perspective on treating inappropriate sinus tachycardia as well as discuss a new hybrid therapy approach and collaborative care for managing patients with IST.
Dr. Beaver discusses the impact to quality of life in patients suffering from symptomatic inappropriate sinus tachycardia as well as treatment options and an overview of the hybrid ablation procedure.
Professor La Meir describes typical symptoms of inappropriate sinus tachycardia, the hybrid ablation procedure and what it means to have a hybrid team approach for the treatment of IST.
Hear how Dr. Dhanunjaya (DJ) Lakkireddy describes patients who suffer from inappropriate sinus tachycardia and what medications have been used to treat symptoms of IST.
Professor de Asmundis walks through common symptoms of inappropriate sinus tachycardia and the hybrid team approach for the treatment of IST.